Prof. Dr. Norbert Polacek Forschungsgruppenleiter Departement für Chemie, Biochemie und Pharmazie Telefon +41 31 684 43 20 Telefon2 +41 31 684 43 43 (Sekretariat) E-Mail norbert.polacek@unibe.ch Büro S075 Postadresse Freiestrasse 3 CH - 3012 Bern Pers. Website polacek.dcbp.unibe.ch
CV Study 1988-1996: studies in Biology/Genetics at the University of Vienna, Austria 1995-1996: diploma thesis in the group of Andrea Barta, Institute of Biochemistry, Vienna (Topic: Identification of divalent metal ion binding sites in rRNA of E. coli) 1997-2000: Ph.D. thesis in the group of Andrea Barta, Institute of Medical Biochemistry, University of Vienna (Topic: Structural dynamics of bacterial rRNA during translation) Career history 2000-2003: Postdoc in the group of Alexander S. Mankin, Center for Pharmaceutical Biotechnology, University of Illinois at Chicago, USA (research field: Ribosomal catalysis) 2003-2005: University Assistant (Assistant Professor) and group leader at the Division of Genomics & RNomics, Innsbruck Medical University - Biocenter, Austria (research fields: Small ncRNAs as ribo-regulators in pro- and eukaryotes, catalytic functions of rRNA) 2005: ‘Habilitation’ (venia docendi) in Molecular Biology at the Medical University Innsbruck 2005-2011: Associate Professor at the Innsbruck Biocenter /Division of Genomics & RNomics, Innsbruck Medical University since 2012: Full Professor of Biochemistry at the Department of Chemistry and Biochemistry / Department of Chemistry, Biochemistry and Pharmaceutical Sciences (since 2021), University of Bern since 2014: NCCR RNA & Disease Delegate Training & Education since 2014: head of the master program in "Molecular Life Sciences" at the University of Bern 2018-2020: Deputy Director of the Department of Chemistry and Biochemistry, University of Bern, Switzerland 2021-2023: Director of the Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Switzerland Prizes and Awards 2006: START award from the Austrian Science Foundation (FWF) 2006: Novartis research prize for Biology 2008: Research award of the Principality Liechtenstein
Research In our group we focus on the functional characterization of non-protein-coding RNAs (ncRNAs) in large cellular RNA/protein complexes, such as the ribosome or the vault particle. We are particularly interested in the structural, catalytic and regulatory roles of ncRNAs during ribosome functioning, translation control, as well as during apoptosis. We approach these aims by applying biochemical, genomic, and bioinformatics tools in model organisms representing all three domains of life (archaea, bacteria and eukarya). Website of the research group
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